This paper examines the role of Customer Relationship Management (CRM) and e-marketing customization in enhancing the competitiveness of food retail stores. It discusses the concept and dimensions of CRM, including operational, analytical, and collaborative aspects. The paper then explores how CRM can provide a deeper understanding of customer needs and behaviors, enabling personalized marketing, improved customer service, and data-driven decision making. However, the implementation of CRM in food retail stores faces challenges related to system integration, data management, staff engagement, and privacy concerns. The paper also highlights the importance of e-marketing customization in meeting individual customer needs, improving satisfaction and loyalty, and developing a competitive advantage. The key mechanisms for implementing e-marketing customization, such as data collection, customer segmentation, personalized content creation, and multichannel integration, are also discussed. The findings suggest that by addressing the challenges and adopting the necessary requirements, food retail stores can effectively leverage CRM and e-marketing customization to enhance their competitive position and drive business growth.