The present work was directed to study the efficiency of some commercially available disinfectants against E.coli O126 and Salmonella Kentucky strains isolated from ostrich' environment. Selected disinfectants represent four different groups of active ingredients that most commonly used in poultry farms. The obtained results showed that after 1 minute contact time,three disinfectants Virkcon-S®, Zix Verox® and Synergize® achieved bactericidal effect as they showed significantly reduction in the growth of E.coli (O126) achieving the 6.38 , 5.21 and 5.38 log reduction respectively . While Ground Zero® failed to achieve 5-log reduction of bacterial population 4.82 after 1 min contact time. Although it can pass and achieve the log reduction at 5, 15 min. On the other hand, S .Kentucky resists the disinfectant at 1 min. contact time and need for increase the contact time or the disinfectant concentration as all the tested disinfectants showed a lower bactericidal effect against S. Kentucky, After 5, and 15 min contact time. All tested disinfectants were able to achieve significant reduction
and inhibition of the bacterial growth.

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