Aging is defined of the process of getting older, or an artificial process to make someone or something look older and loss of function. There has been a global trend toward using of natural phytochemicals present in natural sources as antioxidants and functional foods. Wheatgrass has been proved to contain essential amino acids, active enzymes, flavonoids, chlorophyll, minerals, proteins and vitamins This study was aimed to see the effect of ethanolic and water extracts of wheat grass as natural sources of antioxidants on markers of aging in rats. 36 Sprague-Dawley female rats were obtained. six rats weighing 112 to 125 g considered as control young and therefore the rest of rats weighing 256 to 267 g considered as aged rats their age ranges between 18 month and to 24 month. The rats were divided into 5 groups, the primary and second groups consumed basal diet and thought of as control young and control aged rats, respectively, while the opposite four groups administered ethanolic and water extracts of Wheatgrass powder at doses of 10 and 20 mg for every rat once daily. Blood samples were taken from rats and examined for markers of aging as, the activity of SOD and lipid peroxidation (MDA), total cholesterol, HDL, LDL, VLDL, triglycerides levels and liver functions. Aging resulted during a significant deterioration altogether tested markers of aging including, SOD and MDA, total protein, globulin, albumin HDL-cholesterol. Also, a big increase in, ALT, AST triglycerides, total cholesterol, LDL and VLDL levels was observed during aging. Administering aged rats with Wheatgrass ethanolic and water extracts caused a big improvement within the above markers and returned the abnormal markers back to the traditional levels Approximately as found on top of things young rats especially at 20 mg from wheatgrass. So, it might be recommended that wheatgrass ethanolic extracts (70) might be wont to improve the abnormal changes in health state of aging human and return them to just about the traditional state found in younger human by employing a natural source of antioxidants like Wheatgrass.