The effect of combined use of combelen (Bayer) and My 301 (Glycer yl guaiacolate) was studied in dogs. The clinical signs and some bio chemical changes in the serum were recorded before and 1/4, 1/2, 1, 2, 4 and 24 hours after injection.
During adminstration, the animal gradually lost consciousness and went into a state of complete muscular relaxation. Body reflexes were recorded. A decrease in body temperature, heart beats and respiratory rates were observed shortly after administration of the agent which gradually returned to normal. There were transient change in some serum constituents. After 24 hours all parameters returned to nearly their preanaesthetic values.