The present study was carried out on 42 buffaloes at Beni-Suef. Animals were classiied into 4 groups. Animals in the first group (12) were suffering from pneumonia, while those of the secod group (9) were infested with Fasciola hepatica. The third group (II) suffered from tympany and animals in the fourth group (10) were clinically healthy and served as control. The results revealed that, serum amylase and lipase were greatly increased in buffaloes suffering pneumonia and tympany, but dec reased in fasciola infested animals. At the same time, faecal trypsin was decreased in all investigated diseased buffaloes.
No changes in serum glucose level were shown in animals suffering pneumonia and tympany, while a significant decrease was found in fasciola infested buffaloes.