An outbreak among goats and sheep at Aswan province, Egypt was observed. This outbreak manifested clinically by respiratory, ocular and digestive signs. To identify the cause of this outbreak, 100 goat and 100 sheep were used in the study, some of these animals (70 goat and 45 sheep ) were clinically abnormal while the rest of them (30 goat and 55 sheep) were apparently healthy. These animals examined clinically and serologically. Serological examinations included recent rapid competitive enzyme linked immunosorbent assay (C-ELISA) and virus neutralization test (VNT) in order to detect the antibodies of the suspected aetiological agent of the outbreak. Clinical examination recorded fever, mucopurulent nasal and ocular discharge,erosive stomatitis , diarrhea and pneumonia. Clinical examination proved that linical signs were more severe in goats than sheep. Some infected animals (13 goat and 6 sheep), as showed from serological results, were apparently healthy. 83 examined goat and 51 sheep were positive to rapid C-ELISA while VNT recorded 76 positive goat and 47 sheep. All samples gave positive result with VNT were positive with rapid c ELISA. Clinical findings and serological results proved that the cause of the oubreak was the virus which causes peste des petits ruminants (PPR) in small ruminants. This study proved that rapid C-ELISA and VNT are sensitive techniques in diagnosis of PPR. However, it could be considered that usage of rapid C-ELISA seems faster and more sensitive than VNT. This is the first study concerning diagnosis of PPR by using rapid C-ELISA and the first to compare between rapid C-ELISA and VNT in diagnosis of PPR in Egypt.