To study peste des petits ruminants (PPR) in camels and investigate role played by camels in transmission of PPR virus,50 camel, 50 goat and 50 sheep in contact with camels were used in the study. The animals were belonged to a private animal farm in the Kingdom of Saudi Arabia. These animals were examined clinically, virologically (virus isolation, VI), and by using molecular biology-based technique (Reverse transcription- polymerase chain reaction, RT-PCR). All used animals were clinically healthy as shown by clinical examination performed at the beginning of this work. Clinical examination was done three times a week while VI and RT-PCR were performed twice one month apart. Clinical examination showed that 4 camels were suffered from fever, nasal discharge and cough while 21 goats were suffered from fever, stomatitis, nasal and ocular discharges, diarrhea and pneumonia after two weeks from contact with infected camels. In the first virus isolation, PPR virus has been isolated from 6 camels while no PPR virus could be detected in examined goats and sheep. After performing first RT-PCR, PPR viral nucleic acid was identified in 10 camels but all examined goats and sheep were negative for this technique. PPR virus was isolated from 11 camels and 32 goats while all examined sheep were negative in the second virus isolation. The second RT-PCR showed presence of PPR viral nucleic acid in 17 camel and 35 goat while no PPR viral nucleic acid could be detected in all examined sheep. Results of this work proved that camel is susceptible to PPR and infected camel can transmit PPR virus to other camels as well as camels plays a very important role  in dessimination of PPR virus to contact goats. Dangerous of this role increased by the fact that most infected camels were apparently healthy. This role not proved in sheep examined in this study. Also, our results showed that RT-PCR is faster and more sensitive than VI in diagnosis of PPR So, we recommend using of this technique in routine diagnosis of PPR and in any epidemiological studies concerning PPR as well as using this sensitive assay in examination of camels imported from Sudan to can control and eradicate this disease from Egypt.