One hundred samples of fish represented by 50 samples of Tilapia nilotica and 50 samples of Claris lazera were collected from different fish markets in Alexandria Governorate to evaluate their microbiological quality and detection of food borne psychrotrophs. The bacteriological examination revealed that the mean values of total psychrotrophic count, total Pseudomonas count and total Bacillus cereus count in Tilapia nilotica were 3.2X10² ± 1.3X10², 4.5X10³ ± 1.3X10³ and 3X10³ ± 3.6X10² respectively.     The majority of Tilapia nilotica fish samples had psychrotrophic count ranged from 10⁴ to <10⁵. While, the majority of such examined fish samples had Pseudomonas and Bacillus cereus count between 10³ to 10⁴. Furthermore, the avarage counts of psychrotrophics, Pseudomonas and Bacillus cereus for Claris lazera were 2.5X10⁴±3.6X10³, 6.8X10³±1.2X10³ and 8.6X10²±2.1X10² respectively. The public health significance of the isolated microorganisms and possible sources of contamination of fish with such organisms as well as some recommendations to improve the quality of fish were discussed.