The aim of this work was to use synbiotic as an alternative way to control Eimeria acervulina infections in broilers. One hundred and fifty one-day-old chicks were used. They were divided into 5 equal groups, each of 30 birds. The 1^st group was a negative control. The other groups were directly inoculated intra-crop, with 1x10⁵ sporulated oocysts of E. acervulina on the 8^th day of age. The 2^nd group was kept as positive control. The 3^rd group was fed ration mixed with diclazuril (1 ppm). The 4^th group was fed ration mixed with synbiotic (1 kg/ton feed). The 5^th group was fed ration mixed with diclazuril (1 ppm) plus synbiotic (1 kg/ton). Our findings revealed that, diclazuril plus synbiotic-treated group showed the superior reduction in oocyst output & lesion score. Synbiotic-treated birds showed a significant increase in body weight, gain, feed conversion ratio, serum total protein, albumin and globulin. These birds also showed reduction in serum total cholesterol and triglycerides. It was inferred that, synbiotic could be introduced as a safe and natural tools to control coccidiosis in broilers either with or without diclazuril.