ABSTRACT   Fifty samples of skimmed milk soft cheese were randomly collected from different dairy shops and supermarkets in Cairo and Giza Governorates, Egypt. Collected samples were examined microbiologically for enumeration, isolation and identification of Enterobacteriaceae. The results showed that the mean value of Total Enterobacteriaceae Count was 7.49×10⁷ ± 0.15×10⁷ cfu/g. Escherichia coli could be found in 64% of the examined samples with a mean value of 4.56×10⁷ ± 0.14×10⁷ MPN/g. E.coli serovars O146, O1, O18, O15, O8 and O78 could be detected in a percentage of 2.90, 2.90, 4.34, 1.45, 1.45 and 1.45, respectively. Salmonellacould not be detected. It could be concluded that skimmed milk soft cheese may harbor serious health risk in the study areas.