Beta
168945

IN-VIVO REPLICATION OF CYPRINID HERPESVIRUS-3 IN GOLDFISH

Article

Last updated: 23 Jan 2023

Subjects

-

Tags

Fish production, Aquarium management, and Aquatic Animal Medicine
Virology

Abstract

Cyprinid herpes virus-3 (CyHV-3) is the causative agent of the lethal, highly contagious and notifiable koi herpesvirus disease (KHVD) in common carp and koi. Since its first identification, outbreaks of KHVD have occurred worldwide with significant economic losses in common carp and ornamental koi aquaculture industries. In the present study, experimental infection of goldfish by immersion rout was established. Apparently healthy common carp and goldfish were exposed to various concentrations of the CyHV-3 and monitored for mortality and development of clinical signs. CyHV-3 DNA was detected in the tissues of the challenged goldfish and common carp, which confirm the suitability of the immersion route to be used for infection of goldfish with CyHV-3. In addition, CyHV-3 terminase gene was amplified from the RNA extracted from the goldfish gill tissues at two- and eight-days post exposure to CyHV-3. The primer set used for amplification of this gene is specific for RT-PCR and did not amplify this gene from DNA. Results of this investigation confirm the replication of CyHV-3 in the goldfish tissues, which act as a true carrier not a vector or fomites and establish the experimental infection of goldfish with CyHV-3 by immersion route. 

DOI

10.21608/avmj.2019.168945

Keywords

CyHV-3, KHV, Koi, carp, virus replication

Authors

First Name

HATEM

Last Name

SOLIMAN

MiddleName

-

Affiliation

Department of Aquatic Animals Medicine and Management, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

Email

hatemtoughan@hotmail.com

City

-

Orcid

-

Volume

65

Article Issue

162

Related Issue

24303

Issue Date

2019-07-01

Receive Date

2019-06-30

Publish Date

2019-07-30

Page Start

71

Page End

75

Print ISSN

1012-5973

Online ISSN

2314-5226

Link

https://avmj.journals.ekb.eg/article_168945.html

Detail API

https://avmj.journals.ekb.eg/service?article_code=168945

Order

10

Publication Type

Journal

Publication Title

Assiut Veterinary Medical Journal

Publication Link

https://avmj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

23 Jan 2023