Beta
ManageSearchChatDiscover
175190

Antioxidant activity of <i>Malpighia glabra<i/> L., leaves extract

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pharmacognosy
phytochemistry

Abstract

Malpighia glabra. L (Acerola) fruits have wide global medicinal uses due to rich antioxidant contents. Little studies were carried on other parts of plant. Malpighia glabra. L leaves (1.5 kg) was subjected to soxhlet exhaustive extraction with methanol and concentrated under vacuum. The dried extract was defatted with petroleum-ether then fractionated with ethyl acetate and n-butanol 3 successive times respectively. The ethyl acetate fraction (9 gm) was subjected to series of silica gel and Sephadex LH-20 column chromatography. Phytochemical investigation of the Ethyl acetate fraction of Malpighia glabra. L leaves in this study resulted in separation of four pure compounds (Caffeic acid, Chlorogenic acid, Quercetin & Kaempferol). The structures of the separated compounds were assigned based on NMR spectral data and mass spectrometer analysis. The methanolic extract showed high values of total phenolics (96.36 mg GAE/g), flavonoids (30.71 mg QE/g) and higher antioxidant activity towards DPPH radical with IC50 = 49.8(mg/ml).

DOI

10.21608/aijpms.2021.59935.1042

Keywords

<i>Malpighia glabra<i/> L. leaves, DPPH, Caffeic acid, chlorogenic acid, Quercetin, kaempferol

Authors

First Name

Amany

Last Name

Fekry

MiddleName

-

Affiliation

Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt

Email

a.fekry.sallam89@gmail.com

City

-

Orcid

-

First Name

walaa

Last Name

Elsabbagh

MiddleName

-

Affiliation

Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt

Email

walaaelsabbagh5@gmail.com

City

Cairo

Orcid

-

First Name

Marwa

Last Name

Abu Bakr

MiddleName

-

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt

Email

marwa.elaraby@gmail.com

City

-

Orcid

0000-0003-0798-5394

First Name

Mona

Last Name

El-Ghazaly

MiddleName

-

Affiliation

Department of Drug Radiation Research, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt

Email

monaghazaly@gmail.com

City

-

Orcid

-

First Name

Abd El-Salam

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt

Email

abdelsalam876@yahoo.com

City

Cairo

Orcid

-

Volume

1

Article Issue

2

Related Issue

25720

Issue Date

2021-06-01

Receive Date

2021-01-26

Publish Date

2021-06-01

Page Start

88

Page End

93

Print ISSN

2735-4598

Online ISSN

2735-4601

Article File

AIJPMS_Volume 1_Issue 2_Pages 88-93.pdf

PDF . 315.3kB

Link

https://aijpms.journals.ekb.eg/article_175190.html

Detail API

https://aijpms.journals.ekb.eg/service?article_code=175190

Order

10

Type

Original research articles

Type Code

1,562

Publication Type

Journal

Publication Title

Azhar International Journal of Pharmaceutical and Medical Sciences

Publication Link

https://aijpms.journals.ekb.eg/

MainTitle

Antioxidant activity of <i>Malpighia glabra<i/> L., leaves extract

Details

Type

Article

Created At

23 Jan 2023