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175361

HYPOLIPIDAEMIC EFFECT OF COLD AQUEOUS EXTRACT MIXTURES OF GRAPE (VITIS VINIVERA ) SEED, BASIL (OCIMUM BASILICUM) LEAVES AND MORINGA (MORINGA OLEIFERA) LEAVES IN RATS

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Last updated: 26 Dec 2024

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Abstract

Different mixtures of (Moringa olifera leaves. Ocimum basilcum leaves and Grape seeds) as Mix A (Moringa leaves. basil leaves and Grape seeds), Mix. B (Moringa leaves and basil leaves), Mix. C Moringa olifera leaves and Grape seeds) and Mix D (basil leaves and Grape seeds) were analyzed for its total phenolic, total flavonoids contents, phenolic and flavonoids compounds then oral administration different mixtures with (200 and 100bwmg/k) to 60 sixty albino hypercholesterolemic rats aiming to improve their lipid profile. By the end of the experiment (28days) TC, TG, LDL, HDL, atherogenic indices (AC, CRR, AI) were analyzed.  Mix A contained Total phenolic and Total flavonoid 1.23 and 0.07, Mix B 1.06 and 0.07, Mix C 1.46 and 0.09, Mix D 1.16 and 0.06 respectively.  The highest total phenolic content and flavonoid in Mix C (1.46mg GAE g−1 DW) and flavonoid content (0.0068 mg QE). Narinigin the major compound flavonoid of Mix A. Mix B and Mix C as 2165.36 ppm, 9201.27ppm and2978.04 ppm. While Hesperidin910.17ppm major compound flavonoid of Mix D. The total cholesterol, triglyceride and LDL ratios were improved by 14.98%, 36.93% and 25.09% in groups were treated with Mix A (200mg/kbw) compared with the positive control group. Significant high density lipoprotein (HDL) cholesterol and atherogenic indices (AC, CRR, AI), implying that hypochol-esterolemic effects of Mix. A 200mg/bw of rats were partly attributed to the reduced absorption of lipid and cholesterol.

DOI

10.21608/mjfds.2019.175361

Keywords

Moringa, Basil leaves, Grape seeds- Hypercholesterolemia - Total Phenolics, Total flavonoids, Phenolics and Flavonoids Compounds

Authors

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A.E.

Last Name

EL-Beltagy

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Affiliation

Food Science and technology Department, of Agriculture, Minufiya University, Shebien EL-kom, Egypt.

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First Name

Warda A.

Last Name

Yousef

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Food Science and technology Department, of Agriculture, Minufiya University, Shebien EL-kom, Egypt.

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Volume

4

Article Issue

5

Related Issue

18692

Issue Date

2019-12-01

Receive Date

2021-06-05

Publish Date

2019-12-01

Page Start

153

Page End

169

Print ISSN

2357-0792

Online ISSN

2735-3486

Article File

MJFDS_Volume 4_Issue 5_Pages 153-169.pdf

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https://mjfds.journals.ekb.eg/article_175361.html

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https://mjfds.journals.ekb.eg/service?article_code=175361

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original papers

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1,406

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Publication Title

Menoufia Journal of Food and Dairy Sciences

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https://mjfds.journals.ekb.eg/

MainTitle

HYPOLIPIDAEMIC EFFECT OF COLD AQUEOUS EXTRACT MIXTURES OF GRAPE (VITIS VINIVERA ) SEED, BASIL (OCIMUM BASILICUM) LEAVES AND MORINGA (MORINGA OLEIFERA) LEAVES IN RATS

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Article

Created At

23 Jan 2023