Series of experiments including in vivo, greenhouse and field trials were conducted at Noubariya district, Behera Governorate, Egypt during two successive winter seasons (2009/10 and 2010/11) to investigate the effect of foliar application with some biotic formulas based on effective microorganisms (EM) as resistance inducers for faba bean (Vicia faba L.) growth, total pigments and chlorophyll, yield as well as chocolate spot disease resistance cause by Botrytis fabae. Onion, garlic or cabbage were used to formulate these biotic formulas in EM1 or EM5. Application of these biotic formulas at the concentrations of 4% and 8% significantly suppressed the disease severity and increased total pigments, chlorophyll and phenols contents, enzymes activity and, therefore, plant growth and productivity. Results indicated that when the infection of chocolate spot disease, caused by Botrytis fabae, exists as a serious common biotic stress, the usage of the biotic formulas as inducers is essential as clean development mechanism (CDM) concept to satisfy the needs of the clean agriculture. When the infection alert is existing at the vegetative stage; the foliar application either with (EM5+garlic) 4%, (EM5+onion) 8% or (EM5+onion 4%), respectively, once at 30 days after sowing date is highly recommended. In case of the alert is postponed until the flowering or reproductive stage, foliar application with (EM5+garlic) 8% once at 60 days after sowing date is precisely a must.