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100951

EFFECT OF BINARY BLEND OF VEHICLES ON THE PHYSICAL PROPERTIES OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS

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Last updated: 25 Dec 2024

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Abstract

Directly compressible vehicles such as Avicel, Emdex, Sugratab, Anhydrous Lactose U.S.P, STA-R 1500 starch and Fmcompress, were used either singly or in binary blends in the ratios of 1:1, 1:3 and 3:1 w/w for the preparation diiodoquin tablets. Avicel, Celutab and STA-Rx 1500 starch were found to be the most suitable single vehicles for the formulation of diiodoquin tablets. Tablets produced using STA-R and its blends with the other vehicles, disintegrated within the specified time. The best blends used for the manufacturing of directly compressed diiodoquin tablets were those containing avicel/STA-Rx 1500 starch 3:1 and 1:3. The least actual concentration of the vehicle needed for the preparation of good diiodoquin tablets was not  less than 42.0% w/w.

DOI

10.21608/bfsa.1983.100951

Authors

First Name

A.

Last Name

Ahoutaleb

MiddleName

E.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

Email

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City

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Orcid

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First Name

S.

Last Name

Tout

MiddleName

A.

Affiliation

Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt

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City

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Orcid

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Volume

6

Article Issue

1

Related Issue

15296

Issue Date

1983-06-01

Receive Date

1982-05-09

Publish Date

1983-06-30

Page Start

135

Page End

153

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 6_Issue 1_Pages 135-153.pdf

PDF . 755.5kB

Link

https://bpsa.journals.ekb.eg/article_100951.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=100951

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Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

EFFECT OF BINARY BLEND OF VEHICLES ON THE PHYSICAL PROPERTIES OF DIRECTLY COMPRESSED DIIODOQUIN TABLETS

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Article

Created At

22 Jan 2023