The effect of washing and blanching on the behavior and persistence of chkxpyrifos-methyl, diazinon and phenthoate in Molouldiia was Investigated. The effect of the insecticides on carbohydrates, chlorophyll and soluble protein contents as well as the activity of peroxidase and polyphenol oxidase were also studied. The initial deposit (zero time) the residues on moloukhia were 62.70, 115.74 and 160.86ppm for chlorpyrifos-methyl, diazinon and phenthoate respectively. The residues half life values (121_₅0) for the same pesticides were 14.65, 13.26 and 13.85 hrs respectively. Washing with tap water after one hour of application removed 54.22% of dfiorpyrifos-methyl, 68.98% of diazinon and 71.98 % of phenthoate. The corresponding values after blanching were 79.74, 76.02 and 98.31 % respectively. The results revealed that all tested insecticides treatment did not show any change In the total content of carbohydrates, total soluble sugars, reducing sugars and non-reducing sugar contents, chlorophyll a, b and total chlorophyll contents, total soluble protein contents and peroxidase activity. phenthoate treatment significantly increased in total chlorophyll content. Diazinon significantly decreased in the chlorophyll a, b and total chlorophyll contents. Chlorpyrifos­methyl treatment caused a significant decreased in total soluble protein contents in moloukhia leaves.