Wheat, (Triticum aestivum L.), is a major cereal crop in Egypt. Five commercial wheat varieties: Giza 168, Sakha 93, Beni–Sweif 1, Gemmeiza 7 and Gemmiza 9 were tested at Giza region for susceptibility to the infestation with Atherigona bedfordi during 2006/2007 and 2007/2008 wheat growing seasons. In both seasons, Giza 168 was relatively the most susceptible followed by the other varieties. In the1st season, the infestation means were 19.36, 14.91, 12.73, 10.45 and 9.36% on Giza 168, Sakha 93, Gemmeiza 9, Gemmeiza 7 and Beni-Swif 1, respectively. In the 2nd season, the infestation, except Beni-Swif 1, had a similar trend and the corresponding respective infestation means were 11.17, 8.75, 7.75, 3.58 and 5.08%.