Arabian Oryx belong to bovine species and are the smallest member of the genus Oryx, native to the Arabian Peninsula. The population numbers and the Arabian Oryx frequency distribution at different sites of Bahrain (Al-Areen wildlife Park / Reserve, Al-Areen Wildlife Park / Visitors' Center, and Hawar Island) were 70%, 14%, and 16% respectively. Males represent 29.4%, while females are 70.6% of the total population. Samples have been assembled from apparently diseased Arabian Oryx from three districts in Bahrain where the Arabian Oryx was found, 25 Oryx with positive respiratory signs were tested for Pasteurella multocida, while 30 Oryx with digestive tract signs were tested for Salmonellosis. After the microbiological evaluation, from the 25 animals showing clinical signs, four animals only tested positive for Pasteurella multocida, 3 of them are females and one male and all of them were younger than 1 year of age. The obtained results concluded that Arabian Oryx were adapted to the weather in Bahrain, but they are still susceptible to diseases, especially at young ages. More effort from relevant authorities is required to maintain control of Pasteurella multocida and salmonella infection in Arabian Oryx.