Silkworm is a typical monophagous insect and mulberry (Morus spp.) leaf is its sole feed. The current investigation aims to compare biochemical and economic characteristics of two hybrids of silkworms (B. mori. L.). Two hybrids of Bombyx mori, (L.) (H1xKKxG2xV2) and (Giza B) silkworm larvae were fed on mulberry leaves Morus indica var kanava-2 planted in the experimental farm during the spring season for biochemical and economic studies. Mulberry leaves were offered four times per day. The imported hybrid (H1xKKxG2xV2) showed higher and consistent growth rates than the native hybrid (Giza B) for all the developmental stages. It can be concluded that the selection of strong hybrids from silkworm and feeding on a good variety of Indian cultivar Morus alba var. kanava-2 imported from Indian improves the growth value of biological and economic parameters.