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252687

BIOLOGICAL EFFECT OF HIGH DIETARY FATS AND SUCROSE LEVEL ON LIVER FUNCTIONS AND LIPIDS PROFILE IN THE EXPERIMENTAL RATS

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Last updated: 22 Jan 2023

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Abstract

The effect of a diet containing 25% edible fats (balady butler,balady samna.
and hydrogenated fat); edible oils (corn oil, sunflower oil and mixed oil) and a diet
containing 45% sucrose on body weight gain; organs weight (liver, kidney and
splelen); liver enzymes (AL T and AST); lipid profile (Triglycerides, Total cholesterol
(T.ch.), High density lipoprotein cholesterol (HDL-Ch), Low density Iipoprotein(LDL-Ch)
and Total protein (TP). T he risk ratio is the result 0 f T .ch divided by H DL-ch were
studied in the experimental rats. The feeding experimental was carried out during 45
days and the results were compared with control group of rats fed a balanced diet.
The results showed that groups of rats fed on diet containing (25% edible fat and/or
45% sucrose) caused significant increase in body weight gain, organs weight, level of
liver enzymes and lipid profiles of serum and liver extract, while slightly decreased in
total protein was observed when compared with control. On the other side, data
showed that no changes were observed for groups of rats fed on 25% edible oils on
body weight gain, organs weight, liver enzymes, lipids profile and total protein
comparing with control. While, the tow-tat (5%) group in rats diet yielded a significant
decrease in the all previously parameters than control. this is due to the low fat
content in the feeding diets of rats. In conclusion, although 25% edible oils was high
fat diet. but it was less harmful effect on the liver functions and lipids profile than that
recorded for the 25% edible fats (Saturated fatly acids) and thus it can be represented
the 25% edible oils (unsaturated fatty acids) was healthy diet for the experimental
rats.

DOI

10.21608/jssae.2003.252687

Keywords

Lipid profile, High fat diet, High sucrose diet, liver enzymes, AST and ALT

Authors

First Name

Sh.

Last Name

Kerolles,

MiddleName

Y.

Affiliation

National Organization for Drug Control and Research-Cairo, Egypt.

Email

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City

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Orcid

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First Name

W.

Last Name

EI Malky

MiddleName

A.

Affiliation

National Organization for Drug Control and Research-Cairo, Egypt.

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Orcid

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Volume

28

Article Issue

7

Related Issue

35955

Issue Date

2003-07-01

Receive Date

2003-06-13

Publish Date

2003-07-01

Page Start

5,815

Page End

5,823

Print ISSN

2090-3685

Online ISSN

2090-3766

Link

https://jssae.journals.ekb.eg/article_252687.html

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https://jssae.journals.ekb.eg/service?article_code=252687

Order

8

Type

Original Article

Type Code

889

Publication Type

Journal

Publication Title

Journal of Soil Sciences and Agricultural Engineering

Publication Link

https://jssae.journals.ekb.eg/

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Article

Created At

22 Jan 2023