The purpose of this study was to evaluate the hepatoprotective and antifibrotic potential of ginger, aloe, bee honey and their mixture on chronic liver injury induced by CCIi for 8 weeks. The results exhibited that the increase of serum alanine aminofransferase (SALT). serum aspartate aminotransferase (sAST). alkaline phosphatase (sALP) activities. total and direct biiirubin as well as liver homogenate thiobarbituric acid reactive substances (TEARS) in CCIa liver injury were significantly reduced by treatment with ginger (9.1glkg ow), aloe (0.5glkg b. w). bee honey {as glkg b. w.) and their mixture, five times in a week. The aforementioned materials reduced the collagen content by 69%, 667%. 62.85% and 68.65%, respectively. The results were comparable to silymarin (25mg! kg bw.)