An aggressive isolate of Fusarium solani was obtained from damped-off soybean plants cultivated in the experimental farm, Faculty of Agriculture, Alexandria.             Pathogenicity tests show that the isolated F.solani cause damping-off symptoms. The seedling emergence of the two soybean cultivars, Crowford and Clark was reduced by 79.5, 82.7 % respectively. Trichoderma harzianum and Vitavax-Thiram reduced the damping-off percentage and increased the fresh and dry weight of the two tested cultivars. No significant difference was observed in the treatment with T. harzianum and Vitavax-Thiram.