Two field experiments were conducted during two successive winter seasons of 2012/2013 and 2013/2014 at El-Baramoun farm, Mansoura Horticulture Research station to study the effect of spraying by ATP (100ppm), amino acids (2.5ml/l), glycinebetaine (50ppm), salicylic acid (20ppm), Zinc (100ppm) and Boron (50ppm) compared with tap water (control treatment) on vegetative growth parameters, photosynthetic pigments, mineral constituents,  yield components and fruit quality of  tomato cv. Super strain B grown under low temperature conditions. Significant increases in vegetative growth parameters and photosynthetic pigment contents were recorded relative to corresponding control treatment. ATP treatment was more pronounced in these increments. Marked increases were observed in N, P, K, Ca, Mg and Zn percentages as a result of all applied treatments. However, Zn treatment decreased N and P percentages and gave the highest percentage of Zn during both seasons. B treatment at 50ppm had the highest fruit set percentage, while ATP treatment had the highest yield per plant, early yield and total yield per feddan. In addition, all spraying treatments significantly enhanced tomato fruit quality characters (TSS, TA, VC and lycopene), except for salicylic acid treatment which had no effect on TA (tetratable acidity) relative to control plants. The behavior of most studied traits was not changed from season to other except Chl A, N%, Ca%, F set%, YP, TSS and lycopene indicating the magnitude of the environmental factors on the genetic expression of these traits as controlled by more than one gene. In view of the obtained results, it was found that vegetative growth, yield and fruit quality of tomato plants cv. Super strain B could be enhanced under cold stress condition by spraying by anti-stressor under study (ATP, amino acid, glycinebetain, salicylic acid, Zn or B). It is worthy to mention that ATP spraying treatment at 100 ppm was the most optimum treatment.