77746

Biological Effect of Green Tea on Hypercholesterolemia Level in Rats

Article

Last updated: 04 Jan 2025

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Abstract

The present study is conducted to evaluate the preventive effects of green tea (Camellia sinensis) on rat feed on high fat diet. Twenty-four male albino rats each weighing 100±30g, was divided into 4 groups. Group (1) negative control group feeding basal diet, Group(2)positive control group fed in high fat diet , Group (3) hypercholesterolemic rats fed on basal diet containing 10% green tea  and Group (4) hypercholesterolemic rats fed on basal diet containing tablets atorvastatin. At the end of experiment, the four groups were compared in terms of the proportion of fat in the blood. The results indicated that, high fat diet caused deleterious metabolic effects, including hypertriglyceridemia, and liver dysfunction. Rats fed high fat diet alone showed increased activities of hepatocellular enzymes in plasma, significant decline in antioxidants, and elevated lipid peroxidation indices in liver. Green tea treatment significantly reduced elevated lipid peroxidation product, and brought back the liver antioxidants and the over accumulation lipids in serum towards normal. In addition, results showed that green tea significantly reduced total cholesterol (TC), plasma triglyceride (TG), LDL-C, VLDL-C and elevated plasma antioxidant in green tea treated rats groups (3) compared to group (2). Therefore, the results are clearly indicative of the beneficial effects of green tea in reducing lateral side effects of hyperlipidemia.

DOI

10.21608/jfds.2018.77746

Keywords

High fat fed diet, Green tea (Camellia sinensis), Hyperlipidemia and Hepatic statuses

Authors

First Name

Gehan

Last Name

Ghoniem

MiddleName

A. A.

Affiliation

Food. Industries Dept., Faculty of Agriculture Mansoura University

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Orcid

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First Name

M.

Last Name

Shalaby

MiddleName

T.

Affiliation

Food. Industries Dept., Faculty of Agriculture Mansoura University

Email

shalabym51@yahoo.com

City

-

Orcid

-

First Name

A.

Last Name

Elias

MiddleName

Z. Kh.

Affiliation

Food. Industries Dept., Faculty of Agriculture Mansoura University

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Volume

2018

Article Issue

0

Related Issue

11621

Issue Date

2018-10-01

Receive Date

2020-03-17

Publish Date

2018-10-01

Page Start

7

Page End

12

Print ISSN

2090-3650

Online ISSN

2090-3731

Link

https://jfds.journals.ekb.eg/article_77746.html

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https://jfds.journals.ekb.eg/service?article_code=77746

Order

2

Type

Original Article

Type Code

886

Publication Type

Journal

Publication Title

Journal of Food and Dairy Sciences

Publication Link

https://jfds.journals.ekb.eg/

MainTitle

Biological Effect of Green Tea on Hypercholesterolemia Level in Rats

Details

Type

Article

Created At

22 Jan 2023