Nowadays , Consumption of phenolic-rich food and beverages were widely spread due to their effect against diseases. So, this study was a trial to prepare an untraditional beverage from green tea and sweet basil and biological and chemical properties of each beverage were studied .Results of chemical analysis showed an increase in both of moisture and protein contents in sweet basil ,while observed increase in the amount of ash and carbohydrates in green tea was restricted . Sensory evaluation was conducted for combinations of green tea basil and the mixture containing an equal proportion of green tea and sweet basil(1:1) recorded highest consumer acceptance. Results of bioactive compounds indicated that green tea , sweet basil and their mixture have a high content of total phenolic and flavonoids compounds. But antioxidative effect DPPH not increased up to 70% in green tea and the mixture of green tea and sweet basil(1:1). Results also showed that presence of both Catechol and Catechins were increased in both of green tea and the mixture of green tea and sweet basil up to 1123.50, 985.24 and 987.38, 732.51 ppm, respectively . In addition, biological effect of green tea and sweet basil and their mixture on liver functions and total lipids profile in the blood serum were studied. Experimental rats were treated also with oral dosage with green tea and sweet basil showed non-significant decrease in the activity of ALT (36.91 IU/L) in compared with control sample (26.2 6 IU/L).Also, an improvement in all liver functions in rats treated with green tea and sweet basil against liver function in rats treated by CCl4. Also a marked improvement in lipids profile in blood serum was observed . while , Histopathological examination for liver tissue revealed that a reduction of the effects of injury resulting from liver poisoning with carbon tetrachloride CCL4 by using a mixture of green tea and sweet basil .So, from this present work it could be concluded the possibility of preparing rich phenolic beverage that can protect liver cells and reduce , lipids and cholesterol content through natural bioactive compounds and natural antioxidant effects.