Effect of using celery (Apium graveolens L) for lowering obesity of experimental rats was performed through feeding study using normal and obese rats. Meals used were replaced with 2.5 and 5% celery leaves and seeds powder. The received results showed that: final weight and the efficiency of using feed of the infected rats  (positive control) fed on meals replaced with celery leaves and seeds powder were higher than those of the obese ones and rats fed on standard meal (negative control). In addition, significant differences in weight of liver, kidney, pancreas, heart and spleen to body weight in obese rats fed on meals replaced with celery powder were recorded. Furthermore, the triglycerides found in the bloodstream of rats infected with obesity and fed on meals replaced with celery leaves and seeds powder at 5% level was lower than that of (control positive) at the beginning of the experiment period. There was a significant increase in the level of high-density lipoprotein cholesterol(HDL) for groups of rats fed on meals replaced with celery leaves and seeds powder at the level of 2.5% and 5% compared with positive control, where significant decrease was recorded in (LDL) level in obese rats fed on meals replaced with celery leaves and seeds powder at the levels of 2.5% and 5% compared to positive control. Obese rats fed on meals replaced with 2.5% and 5% of celery powder were characterized by a high improvement in the level of liver enzymes activity (ALT, AST) compared to the control groups. The greatest increment in insulin was found in the group of rat infected with obese which fed on meals replaced with 2.5% and 5% celery powder compared to the control one (positive infected).