The present study was performed to evaluation the microbiological quality of processed packed juices like mango, guava, apple and cocktail purchased from five different local companies in Egypt. The microbiological analysis including total plate count (T.P.C), total coliforms (T.C), faecal coliforms (F.C.), lactic acid bacteria (L.A.B), yeasts, Escherichia coli, Staphylococcus aureus and Clostridium perfingins. The effect of leuconostoc mesenteroids on growth of E. coli and Staph aureus  in vitro was evaluated. The results revealed that microbiological counts in the examined samples were ranged from 1x10 to 5.5x10⁵cfu/ml for T.P.C., 3x10 to 2.5x10⁵ cfu/ml for T.C, 1x10 to 10x10⁵ cfu/ml for yeasts. All the examined samples were negative for E. coli, Staph aureus, Colostridium perfringins and faecal coliforms. The treatment with lecuonostoc mesenteroids induced complete eliminate of E. coli in mango, apple and cocktail juices and Staph aureus in mango and apple juices. The bacteria density of the same microorganisms (E. coli and Staph aureus) were decreased on enrichment broth.