The aim of this study was to evaluate the effect of including three transgenic corn hybrids in broiler diets with the corresponding isogenic corn diets on broiler performance, blood characteristics and histological status for both liver and kidney. Two hundred and fifty two chicks (Ross 308) were fed for 35 days with diets containing Bt or isogenic corn. Both Bt and isogenic corn were analyzed for chemical composition and total aflatoxin contents. The analysis has shown that the amino acid balance for the tested corn was relatively similar to their crude protein content. The diets were formulated to be iso-caloric and iso-nitrogenous and covering the chick requirements as recommended by the management guide data (Ross). The different in chemical composition between corn used in this study is considered as a natural variation. Also, the results showed that both Bt and isogenic corn were free from aflatoxins. The results of the growth study showed no differences in performance parameters. No differences were detected in blood characteristics or histological structure of both kidneys and liver between groups fed the three transgenic corn and their corresponding isogenic corn. Accordingly, it is clear that the transgenic corn had no deleterious or unintended effects on production traits of broiler chickens in this study.