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186357

RESIDUES OF FURAZOLIDONE IN RAW AND BOILED EGGS AFTER ITS ADMINISTRATION TO LAYING HENS

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Last updated: 04 Jan 2025

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Abstract

Furazolidone residue in raw and boiled eggs were measured after administration of the prophylactic dose (20 mg/kg b. wt. for 10 successive days) and the therapeutic dose (35 mg/kg b. wt. for 7 successive days) to laying hens and the clearance time of the drug in the laid eggs was also estimated. The concentration of Furazolidone residue in raw eggs of the prophylactic group was zero in the first day of dosing, in the 2nd day of dosing the concentration was 0.12ug/gm albumin and 0.09 ug/gm yolk and increased gradually to the peak at the 10th day of drug administration (0.41 ug/gm albumin and 0.39 ug/gm yolk. This level declined gradually till reached zero after 6 days in egg albumin and 7 days in the egg yolk from last dosage. Meanwhile, the boiled eggs showed low Furazolidone residues than raw eggs. As far the therapeutic dose groups, Furazolidone residues were detected at the 2nd day of dosing at concentration of 0.18 ug/gm albumin and 0.13 ug/gm yolk and increased to the peak at 7th day (0.50 ug/gm albumin and 0.40 ug/gm yolk) and declined till reached zero after 6 days in the egg albumin and 7 days in egg yolk. In boiled eggs the residues of Furazolidone were lower than in raw eggs.

DOI

10.21608/zjps.1995.186357

Authors

First Name

Mohamed

Last Name

Khairy

MiddleName

-

Affiliation

Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Email

mohamed.khairy@yahoo.com

City

-

Orcid

-

First Name

Ferial

Last Name

Soliman

MiddleName

-

Affiliation

Animal Health Research Institute, Dokki, Cairo, Egypt

Email

ferial.soliman@yahoo.com

City

-

Orcid

-

First Name

Mostafa

Last Name

Abd El Aziz

MiddleName

-

Affiliation

Department. of pharmacology, Faculty of Veterinary Medicine, Zagazig University.

Email

mostafa.abdel-aziz@yahoo.com

City

-

Orcid

-

First Name

Sawsan

Last Name

El-Sheikh

MiddleName

-

Affiliation

Department of Pharmacology, Faculty of Vet. Medicine, Zagazig University

Email

sawsan.el-sheikh@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Ahmed

MiddleName

-

Affiliation

Department. of pharmacology, Faculty of Veterinary Medicine, Zagazig University.

Email

mohamed.ahmed@yahoo.com

City

-

Orcid

-

Volume

4

Article Issue

1

Related Issue

24771

Issue Date

1995-06-01

Receive Date

1995-03-24

Publish Date

1995-06-01

Page Start

84

Page End

88

Print ISSN

1110-5089

Online ISSN

2356-9786

Link

https://zjps.journals.ekb.eg/article_186357.html

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https://zjps.journals.ekb.eg/service?article_code=186357

Order

13

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

RESIDUES OF FURAZOLIDONE IN RAW AND BOILED EGGS AFTER ITS ADMINISTRATION TO LAYING HENS

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Article

Created At

22 Jan 2023