This experiment was conducted throughout the two successive seasons of 2018 and 2019 at Fruit Nursery of Horticulture Department, Faculty of Agriculture at Moshtohor, Benha University Qalyubeia Governorate, Egypt., to study the effect of organic (compost) and NPK biofertilization application as partial replacement for chemical fertilization on vegetative growth, nutrient status of fig transplants "Sultani" cv. at one-year- old. Treatments were the combination of seven fertilization levels (full recommended dose of NPK only (100%NPK) T1, 75% NPK + 25% organic (compost) T2, 50% of NPK+ 50% organic (compost) T3, 25% of NPK+ 75% organic (compost) T4, T5 ( T2+ Bio- NPK), T6 ( T3+ Bio- NPK) and T7 (T4+ Bio- NPK). The result indicated that, application of T1 (100% of chemical NPK) caused a significant increasing in the rate of length, diameter, number of leaves, leaf area, transplant leaves area, fresh and dry weight of  leaves, Leaf dry matter percentage. Likewise, T1 increased the nutrient status i.e. (N, P, K, Mg, Ca, Fe, Mn, Zn), as well as improved the leaf photosynthetic pigments. Followed by T5 75% NPK + 25% organic (compost) + Bio- NPK. By contrast, T4 25% of NPK+ 75% organic (compost) led to the lowest values compared other treatments in both season.