This study was conducted Mirabilis Jalapa and Dragonhead leaves and seeds to evaluate bioactive components. Carbohydrates represent the major component in the Mirabilis.J (75.20%).The content of Dragonhead Lipids and protein (28.5 – 23.9 %) was higher than that of Mirabilis.J (4.5 – 10.4%) respectively. Mirabilis.J and Dragonheadoil contains high amounts of unsaturated fatty acids. The unsaturated fatty acids of Mirabilis.J and Dragonheadoil were (79.21 and 88.55%) of total fatty acids respectively. The major unsaturated fatty acids in Mirabilis.J were linoleic acid (31.48%) followed by oleic (20.38%) and Gama linolenic (18.39%), while, total saturated fatty acids content was 17.87%. Dragonhead seed oil contains also major unsaturated fatty acids were Alfa-linolenic (51.88%) followed by linoleic (23.38%) and oleic acid (12.16%). Total phenolic and total flavonoid compounds, scavenging radical effect on 2, 2-diphenylpicrylhydrazyl (DPPH) and ABTS (2,2-azino-bis (3-ethlbenzthiazoline-3-sulfonic acid) radical-scavenging activity were investigated .The specific phenolic and flavonoid composition quantification for ethanolic extract were performed by HPLC. presence 21 phenolic compounds in dragonhead ethanolic extract. The highest quantities were , ellagic, benzoic, salycillic, ferulic, iso-ferulic and catechein while in Mirabilis.J ethanolic extract were pyrogallol, catechein, salycillic ,chlorogenic, ellagic and benzoic acid were found as the major phenols. Naringin, kamp.3, (2-p-comaroyl) glucose, luteolin.7glucose, hespirdin, rutin, apig.6arbinose.8.galactose, apigenin.-7 -ᴏ-neohes and quercetrin were found as the major flavonoids in dragonhead ethanolic extract however naringin, hespirdin, kamp.3, (2comaroyl) glucose and rutin were found as the major flavonoids in Mirabilis jalapa.