Unsurprisingly, the potential antioxidant means potential pregnancy outcomes. Punicalagin as potential antioxidant is demanded for reproductive health and progesterone adequacy is necessity for maintaining pregnancy in young does. So, the aim of study was to investigate effects of punicalagin (PL) and its combination with human choronic gonadotropin (HCG) on maternal live body weight (MLBW), number of services/conception (NS), conception rate (CR), gestation length (GL), kindling rate (KR),total litter size (TLS), live litter size (LLS), kit weight (KW), progesterone (P4) and estradiol-17(E2) concentrations at 1^st and 2^nd pregnancy of young does. A total of 28 healthy virgindoes (6 months old) were divided into 4equal groups. Group I, each doe was injected IM with 100 ug PL twice/week pre-mating and one time 3 days post-mating.Group II, each doe was injected IM with 25 IU human gonadotropic hormone (HCG) one time 3 days post-mating.Group III, each doe was injected IM with combination PL+HCG. Group IV,each doe was injected IM with sterilized water (control). Blood samples were taken at pre-mating, mating, post-mating, throughout pregnancy and immediately post-kindling for assaying P4 and E2. All does were naturally mated with fertile bucks. Results revealed that PL and combination groups displayed their significant impacts on MLBW, NS/conception, CR, GL, KR, TLS, LLS, KWs (birth and weaning), P4 and E2 concentrations either at 1^st/2^nd pregnancy or both of them. Conclusively, PL and PL+HCG improved pregnancy outcomes of young does particularly at 2^nd pregnancy and could be recommended in rabbit's farms.