In this Present study was conducted in farmed fish in Kafr El- Sheikh City to find out the chemical evaluation of the quality of most famous types of fish in Kafr El- Sheikh City to determine the nutritional value of these cultured freshwater fishes. Quality indices were evaluated in 90 samples from three different fish species collected randomly from farms of Kafr El-Sheikh city (Mugil cephalus, tilapia niloticus and Clarias gariepinus) 30 of each were collected from different farms in Kafr El –Shiekh city, Egypt. Results of pH, total volatile nitrogen (TVN) "mg N /100g", Trimethylamine (TMA)" mg /100g", Thiobarbituric acid (TBA)" mg/kg" and Histamine mg ̸100g''. Result for Tilapia niloticus were ''5.20±.154, 28.55±3.09,4.09±0.24, 3.50±0.144,15.49±2.05", respectively for Mugil cephalus were" 5.25±0.112,21.68±1.53, 3.31±0.351, 2.21±0.252, 11.39±1.43" respectively, for Clarias gariepinus were '' 9.20±1.74, 25.98±1.91, 4.36±0.543, 2.02±0.276, 17.18±2.24'' respectively. This study, can show the nutritional quality and freshness of Tilapiai niloticus,Mugil cephalus and Clarias gariepinus.