Campylobacter species are basic bacterial microbes that cause gastro enteritis in people, both in most industrialized and most creating countries. Campylobacter has been recuperated from chicken corpses, poultry meat parts and supplies in preparing plants worldwide. The regularly announced pathogenic species is C. jejuni representing over 90% of the cases, trailed by C. coli speaking to 7% of the diseases, with the remainder of cases being chiefly C. lari and C. fetus.The objective of this investigation is to decide the prevalence of Campylobacter spp. in some poultry items by utilizing both traditional and recent strategies. One hundred and twenty chicken samples were gathered from different grocery stores at Menofia governorate (25g of every one)taken of chicken breast, thigh, liver and gizzard are taken without any pollution or careless. Most examples were debased with Campylobacter spp. Chicken liver indicated the most elevated defilement item (56.67%) trailed by gizzard(53.33%), thigh (30%) and breast (23.33%) gradually.The level of antimicrobial resistance rate of C.jejuni to cephalothin, oxytetracycline, erythromycin, nalidixic acid, ampicillin ,gentamicin,streptomycin,ciprofloxacin,neomycin,chloramphenicol were 22.2%,33.3%,94.5%,77.8 % ,11.1% ,5.5%,100%,44.4%,61.5and44.4% individually.