A total of 100 healthy balady ducklings, one day old were divided into 4 equal groups (25 in each), Gp (1) kept as control
group, Gp (2 and 3) received 0.5 mg ochratoxin/kg ration and 0.5ml antiochratoxin/liter drinking water for 30 consecutive
days respectively and Gp (4) received both ochratoxin and antiochratoxin in same dose, period and route of administration.
Ducklings supplemented with ochratoxin displayed significant reduction in weight gain, feed conversion rate, RBCs,
WBCs, Hb, PCV, T protein albumin, globulin, T. lipid, cholesterol, triglycerides CAT and SOD, coupled with significant
elevatoin in feed conversion rate, mortality rate, AST, ALT, ALP, uric acid, creatinine and MDA Ducklings received antiochratoxin
showed significant increase in weight gain, RBCs, Hb, total protein, albumin Catalase and super oxide dismutase
beside in signif- icant increase in PCV,WBCs, globulin, AST, ALT, ALP, uric acid and creatinine, triglycerides cholesterol
and total lipid coupled with insignificant decrease in MDA and improved in feed conversion rate. Hemato-biochemical
profiles and antioxidant revealed significant improvement in antiochratoxin treated duckings when compared with
ochratoxinated duckings. Ochratoxin residues in liver and kidney were high at 1^st day of clearance period and disappeared
at 10^th days of clearance period. Alteration in histological picture in internal organ in duckling received ochratoxin revealed
massive degenerative changes in renal epithelial cells of proximal and distal convoluted tubules (Nephrotoxicity) and
massive necrosis of some tubular epithelial cells. Beside severe hepatic damage and also lesions in the immune organs and
intestine. In general, histological changes were mild in birds receiving antiochratoxin alone or with ochratoxin. It could be
concluded that, ochratoxicosis in duckling resulted in poor feed intake, weight gain and feed conversion rate, had adverse
effect in body weight, hemato-biochemical parameters beside decreased blood antioxidant; anti-ochratoxin improved these
parameters in duck