Sandwich panels give an optimum and proven tools to handle problems related to design and analysis of the structures subjected to blast load. The present work focuses on estimating the relative density of steel honeycomb sandwich panels. These panels can be applied on defense works, homeland security, banks and civilian industries intended to minimize the effects of accidental explosions. Sandwich constructions with metallic hexagonal honeycomb core are utilized in this paper due to its high specific strength and stiffness relative to its weight. Estimating the relative density of the metallic hexagonal honeycomb core based on single degree of freedom and the scaling dimensional and considering the dynamic factor contrived under transient dynamic loads resulted from detonating any amount of TNT at any stand-off distance. The strength and stiffness of simply support honeycomb core panels were evaluated based on boundary condition of strength and deformation. The proposed approach suggested controlling the safety design for those panels.