Hundred and thirty eight (138) bacteria were isolated from 3 different
areas on Red Sea governorate, Egypt. Among these 138 moderately halophilic isolates,
2.17%, 3.6%, 6.5%, 9.4%, and 7.2% of the isolates were resistant up to 5mM Cd²⁺
and Zn²⁺ , 20 mM
for Cu²⁺, Pb²⁺, and Co²⁺, respectively. The
majority of halophilic bacterial isolates showed resistance to more than 10 mM
to these metals except Cd²⁺. All strains were resistant to lead,
whereas 50% only of the strains were resistant to cadmium. The resistance to (Cd²⁺ + Cu²⁺); (Zn²⁺
+ Cu²⁺) showed the highest values between bacteria (6.5%), whereas
4.34% of the isolated strains were resistant to (Cd²⁺, Zn²⁺)
and (Zn²⁺ + Pb²⁺), but 2.17% of the isolates were
resistant to 3 metals (Cd²⁺, Zn²⁺ , Cu²⁺); (Zn²⁺
, Cu²⁺, Co²); (Cu²⁺, Co²⁺, Pb²⁺)
and resistant to 4 metals (Zn²⁺ , Cu²⁺, Co²⁺,
Pb²⁺); (Cd²⁺, Zn²⁺ Cu²⁺, Co²);
(Cd²,Zn²⁺ , Cu²⁺, Pb²⁺); (Zn²⁺,
Pb²⁺ ,Cu²⁺, Co²). No bacterial isolates were
resistant to the 5 metals combined. The isolated halophilic bacteria exhibited sharp peaks of
resistance to drugs such as: Velosef 95%, Cceftriaxone, 91.66%, Ampicillin
83.33 %, Nitrofurantion 81.66%, Tarivid 80%, Cephalothin 73.33%, Cephalexin
66.66%, Cefadroxil 83.33%, and Flucloxacillin 85% whereas  few 
isolates (6.6%)  were  resistant 
to  Vancomycin.