Background:The Sleep-Wake Cycle driven by Circadian Rhythm is an important physiological happening in our body. Medical students are having a great academic load which could lead to their poor quality of sleep. Medical students especially First MBBS students suffer from sleep deprivation. It has been found that the Sleep-Wake Cycle of medical students is characterized by delayed onset of sleep, reduced sleep duration, and excessive daytime sleepiness. These kinds of sleep disturbances will affect their Academic performance. Objectives: To find out the Prevalence of Sleep disorders among First MBBS medical students and to find its relationship with their academic performance. Methodology:It is a cross-sectional study done among the 100 First year MBBS Students during the period of 2020-2021. After obtaining the Institutional Ethical Committee Clearance their demographic details were obtained. The sleep quality was assessed by the Pittsburg sleep quality index (PSQI) Scale. The Academic performance was assessed by finding out the average of their internal assessment marks conducted by the 3 first-year departments over the past month. Data was entered in MS excel and analysis was done in SPSS 23 software. P value Results:In our study, around 66% of the students had poor quality sleep. It was found that there was a significant relationship between sleep quality and academic performance. Conclusion:Identification and early intervention of sleep disorders among First MBBS medical students will help in improving their academic performances.