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18809

New Photo probe for Assessment of Norepinephrine in Pharmaceutical Formulation and Serum Samples

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Last updated: 03 Jan 2025

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Abstract

           A simple, sensitive and selective spectroflourimetric method for the determination of Norepinephrine (NE) is developed. The method depends on the enhancement of the fluorescence intensity of the photo probe at 351 nm in presence of different concentrations of NE in acetonitrile, at λex = 290 nm at pH 5.01. The enhancement of the emission band of the photo probe at 351nm was found to be directly proportional to the concentration of NE with a dynamic range of 1 x 10-5 – 4.4 x 10-8 mol L−1 and detection limit of 2.3 x 10-8 mol L−1. This method is simple, accurate and can successfully be applied to the determination of NE inpharmaceutical formulation and serum samples with remarkably satisfactory results.
 

DOI

10.21608/jsrs.2015.18809

Keywords

norepinephrine, Photo probe, enhancing, Fluorescence Intensity

Authors

First Name

Mona

Last Name

Ahmed

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Girls for Arts, Science and Education, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Attia

MiddleName

S.

Affiliation

Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

H.

Last Name

Hefny

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Girls for Arts, Science and Education, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Manara

Last Name

Ayoub

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Girls for Arts, Science and Education, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Mona

Last Name

Mohammed

MiddleName

N.

Affiliation

Chemistry Department, Faculty of Girls for Arts, Science and Education, Ain Shams University, Cairo, Egypt

Email

mona.na66@yahoo.com

City

-

Orcid

-

Volume

32

Article Issue

part 1

Related Issue

3825

Issue Date

2015-12-01

Receive Date

2018-11-12

Publish Date

2015-12-01

Page Start

238

Page End

253

Print ISSN

2356-8364

Online ISSN

2356-8372

Article File

JSRS_Volume 32_Issue part 1_Pages 238-253.pdf

PDF . 11.0MB

Link

https://jsrs.journals.ekb.eg/article_18809.html

Detail API

https://jsrs.journals.ekb.eg/service?article_code=18809

Order

14

Type

Original Article

Type Code

656

Publication Type

Journal

Publication Title

Journal of Scientific Research in Science

Publication Link

https://jsrs.journals.ekb.eg/

MainTitle

New Photo probe for Assessment of Norepinephrine in Pharmaceutical Formulation and Serum Samples

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Type

Article

Created At

22 Jan 2023