Background: Microneedling (MN) has been used to treat scars, rhytides, and dyschromia, among other dermatological conditions. Small channels of dermal as well as epidermal damage are created by puncturing the skin with needles. After being damaged collagen is removed, then new growth and remodeling. Neovascularization and neocollagenesis are aided by elastic fiber formation and fibroblasts as well as platelet-derived growth factors. In the end, scars, particularly atrophic scars, will look better. Cytokines such as interleukin-1 alpha, interleukin-6, tumor necrosis factor-alpha, and granulocyte and macrophage colony-stimulating factor are released quickly after microneedling, and keratinocyte migration as well as vasodilation occurs to heal micropunctured epidermal damage. Objective: This review article aimed to discuss general overview of microneedling and assessment of its uses in dermatology. Methods: Microneedling, and Dermatology, were all looked for in PubMed, Google scholar, and Science direct. References from relevant literature were also evaluated by the authors, but only the most recent or complete study from January 2000 to May 2021 was included. Due to the lack of sources for translation, documents in languages other than English have been ruled out. Papers that did not fall under the purview of major scientific investigations, such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations were omitted. Conclusion: Percutaneous collagen induction therapy, or microneedling, is a cutting-edge non-surgical method that involves puncturing the skin with a series of extremely thin needles in a short time. This approach has garnered widespread support among practitioners of many therapeutic modalities (cheap, effective procedure, which don't need much experience, safe and simple).