Background: A caesarean section is recommended when vaginal delivery is a threat to the mother or child. Aim of study: The aim of the study was to compare the effect of position (sitting versus left lateral) during spinal anesthesia application in cesarean section. The sample of the study was 60 patients. Patients and Methods: Half of the patients received spinal analgesia consisting of 2 ml (10 mg) of 0.5% hyperbaric bupivacaine and 25μg fentanyl in the sitting position, while the other half received spinal analgesia consisting of 2 ml (10 mg) of 0.5% hyperbaric bupivacaine and 25μg fentanyl in the left lateral position. Results: both Left lateral and sitting position in spinal anesthesia in cesarean section have the same effect on hemodynamics, also satisfactory sensory and motor block can be achieved in both positions. So left lateral position is safe and can be performed in parturient who are sedated, in pain or using entonox. Conclusion: Satisfactory sensory and motor blockade were successfully achieved in both sitting and lateral positions during intrathecal injection in cesarean section without significant difference in the hemodynamic changes or motor blockade. With superiority of faster onset of sensory blockade in lateral position, while sitting position is more comfortable for he parturient.