144652

Self - Emulsifying Drug Delivery System: A Novel Approach for Oral Delivery of Poorly Water Soluble Drugs

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Drug design and formulation

Abstract

Self nano emulsifying drug delivery systems (SNEDDs) gained much attention in the last decades since, such systems considered one of the most favorable and efficient approaches to enhance solubility, increase drug absorption and hence, enhance its oral bioavailability of poorly water soluble (lipophilic) drug moieties. Owing to their unique properties and advantages over the other conventional dosage forms, many literatures investigate the change physicochemical properties, pharmacokinetic and pharmacodynamics of self emulsifying formulation compared to both pure drug and its conventional dosage form and always reported significant improvement using SNEDDs. This review discus the composition, advantages and mechanism of action of liquid SNEDDs and some techniques used for solidification of liquid formulations to overcome its drawbacks.

DOI

10.21608/rpbs.2021.52929.1086

Keywords

oral bioavailability, Self nanoemulsifying drug delivery systems, poorly water soluble drugs

Authors

First Name

Ahmed

Last Name

Nasef

MiddleName

Mohammed

Affiliation

Department of pharmaceutics, Faculty of pharmacy, Suez Canal University, Ismailia, Egypt

Email

a_nasef888@yahoo.com

City

-

Orcid

-

Volume

5

Article Issue

Pharmacology-Pharmaceutics

Related Issue

20377

Issue Date

2021-01-01

Receive Date

2020-12-09

Publish Date

2021-01-01

Page Start

52

Page End

58

Print ISSN

2536-9857

Online ISSN

2535-2091

Link

https://rpbs.journals.ekb.eg/article_144652.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=144652

Order

6

Type

Mini-reviews

Type Code

534

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

Self - Emulsifying Drug Delivery System: A Novel Approach for Oral Delivery of Poorly Water Soluble Drugs

Details

Type

Article

Created At

22 Jan 2023