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98602

B:Chemical Investigation of the Red Sea Gorgonian Coral Rumphella torta

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Chemistry of natural products

Abstract

Natural products can provide new structures for medicinal products which can't be obtained from other sources such as combinatorial synthesis. Aquatic environment provides a countless and varied source for new drugs to combat major diseases. It also affords an ecological advantage that includes a diversity of marine plants and animals. Marine invertebrates are known to develop secondary metabolites that may have potential as candidates for new drugs. Recent studies show that octocorals, like gorgonians can generate secondary metabolites which have powerfull pharmacological activities. In this work, chemical investigation of the gorgonian coral Rumphella torta, collected from the Red Sea led to isolation of eight known compounds which are firstly reported from the species, Cholesterol (1), four fatty acids, Myristic acid (2), Palmitic acid (3), Arachidic acid (4) and Stearic acid (5), Chimyl alcohol (6), Hexadecanoic acid 2, 3-dihydroxy-propyl ester (7) and Thymine (8). The structures of these isolated compounds were determined by spectroscopic methods, including 1D and 2D-NMR, as well as mass spectrometry and by comparison to the literature.

DOI

10.21608/rpbs.2020.29811.1062

Keywords

Gorgonian coral, Rumphella torta, Chimyl alcohol, ester, Thymine

Authors

First Name

Nermeen

Last Name

Abdul Kader

MiddleName

Azmy

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt

Email

nermeenazmy25@gmail.com

City

Al ismailia

Orcid

-

First Name

Eman

Last Name

Habib

MiddleName

Sanad

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt

Email

emy_197@hotmail.com

City

-

Orcid

-

First Name

Hashem

Last Name

Hasanean

MiddleName

Abdelhameed

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt

Email

hasanean2000@yahoo.com

City

-

Orcid

-

First Name

safwat

Last Name

ahmed

MiddleName

abd elmaasode

Affiliation

pharmacognosy department,faculty of pharmacy,Suez canal university,Ismailia,Egypt.

Email

safwat_aa@yahoo.com

City

ismailia

Orcid

-

First Name

Reda

Last Name

Abdelhameed

MiddleName

F.A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt

Email

omarreda_70@yahoo.com

City

ismaili

Orcid

-

First Name

Amany

Last Name

Ibrahim

MiddleName

Kamal

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt

Email

am_kamal66@yahoo.com

City

-

Orcid

-

Volume

4

Article Issue

2

Related Issue

14947

Issue Date

2020-07-01

Receive Date

2020-05-08

Publish Date

2020-07-01

Page Start

16

Page End

24

Print ISSN

2536-9857

Online ISSN

2535-2091

Link

https://rpbs.journals.ekb.eg/article_98602.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=98602

Order

7

Type

Original Article

Type Code

532

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023