The experiment was conducted to investigate the effect of incorporating treated Jojoba meal (JM); to mainly replace SM; in broiler diets at different levels 0 (control), 4, 7 and 10% on productive performance, some blood constituents, carcass characteristics, carcass chemical compositions, histological examination of small intestine as well as the economical efficiency of Cobb broiler chickens during the fattening period. Chicks with an average weight of (167.48±0.26 g/chick) stocked at a rate of 10 bird/ m2 for 42 days of experimental period. A total number of 180 chicks were randomly distributed into 4 dietary experimental groups (N=45) in each three replicates (n=15). The experimental diets were formulated to contain 0 (control), 4, 7 and 10% treated JM. All diets were nearly isocaloric (3200 ME kcal/kg) and isonitrogenous (23% and 20% CP for starter and grower periods, respectively).Comparing the chemical composition of treated JM with SM, it appears that JM is rich in its amino acids contents similar with SM, implying that it's a good source of amino acids, although it contains low CP compared with SM. While, JM has higher GE and ME contents than SM, with a low crude fiber compared with SM. The addition of JM had no negative effects on growth performance, where insignificant differences among the experimental groups were observed for LBW at 42 days of age. However, the extraction of antinutritional factors from JM appeared to improve palatability, consequently feed intake was significantly (P≤0.05) increased due to inclusion JM in the diets. The best FCR was observed for birds fed 10% JM compared with other groups. Furthermore, the highest (P≤0.05) total edible parts values were observed for birds fed 10% JM. Abdominal fat percentages were significantly (P≤0.05) decreased due to feeding JM compared to the control group. Inclusion of JM causes significant (P≤0.05) decreases in EE%, of carcass, while CP % was insignificantly affected. However, the addition of JM in broiler diets resulted in benefits effects in decreasing blood lipids profile and increased blood protein fractions, reflecting good physical conditions of the birds.