Beta
ManageSearchChatDiscover
28395

Experimental Study of Bone Defect Repair Using Centrifuged and Non-Centrifuged Bone Marrow Aspirate

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Oral and Maxillofacial Surgery

Abstract

Purpose
this study was conducted between 2015 and 2017 at the faculty of Veterinary Medicine Cairo University and aimed to histologically compare between the effect of processed and unprocessed bone marrow aspirate on the quantity and quality of the newly formed bone.
 
Material and methods 72 Adult male white New Zealand rabbits were used in this study and were divided equally into 2 groups A and B. Bone defects were created at the medial upper extremity of right and left tibia of all rabbits down to bone using trephine bur measuring 4 mm diameter to 5 mm depth. The bone defects were treated with whole bone marrow loaded on gel foam in group A right tibias and using mononuclear cell layer obtained through centrifuging bone marrow loaded on gel foam in group B right tibias. Bone defects in the left tibias in all rabbits treated with gel foam only. Scarification was done 3,6,12 weeks postoperative. Histological evaluation was done using H and E and Masson's trichrome stain.
 
Results
the results showed that group A right tibial defects had better healing results than group B right tibial defects all over the follow-up period, but the differences were not statically significant.
Conclusion
the study findings indicate that the centrifugal concentration techniques provide better therapeutic outcomes over the whole BMA, but it is statistically insignificant.

DOI

10.21608/adjg.2019.28395

Keywords

bone, centrifuged, marrow, non-centrifuged, STEM

Authors

First Name

Hanaa H

Last Name

El-Marzouky

MiddleName

-

Affiliation

Dentist at Egyptian ministry of health,

Email

-

City

-

Orcid

-

First Name

Fatma A

Last Name

Khalifa

MiddleName

-

Affiliation

Associate Professor of oral and maxillofacial Surgery Faculty of Dental Medicine for Girls' Al Azhar University,

Email

-

City

-

Orcid

-

First Name

Ghada A

Last Name

Khalifa

MiddleName

-

Affiliation

Professor Of oral and maxillofacial Surgery Faculty of Dental Medicine for Girls' Al Azhar University,

Email

-

City

-

Orcid

-

First Name

Ashraf A

Last Name

Shamaa

MiddleName

-

Affiliation

Professor of Surgery Anesthesiology and Radiology Faculty of Veterinary Medicine Cairo University,

Email

-

City

-

Orcid

-

First Name

Mona H

Last Name

Farid

MiddleName

-

Affiliation

Professor of Oral Biology Faculty of Dental Medicine for Girls' Al Azhar University,

Email

-

City

-

Orcid

-

First Name

Shadia

Last Name

ELsayed

MiddleName

-

Affiliation

ِِAssistant professor of oral and maxillofacial surgery, faculty of Dental Medicine for Girls' Al Azhar University, cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

5063

Issue Date

2019-01-01

Receive Date

2019-03-05

Publish Date

2019-01-01

Page Start

61

Page End

66

Print ISSN

2537-0308

Online ISSN

2537-0316

Article File

ADJG_Volume 6_Issue 1_Pages 61-66.pdf

PDF . 696.6kB

Link

https://adjg.journals.ekb.eg/article_28395.html

Detail API

https://adjg.journals.ekb.eg/service?article_code=28395

Order

3

Type

Original Article

Type Code

488

Publication Type

Journal

Publication Title

Al-Azhar Dental Journal for Girls

Publication Link

https://adjg.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023