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255461

The Potential Protective Effects of Aqueous Extracts of Some Herbs on Renal Toxicity Induced by Formaldehyde in Experimental Rats

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Nutritional quality of novel foods

Abstract

The current study was performed to evaluate the protective effect of aqueous extracts of Corn silk and Asparagus Officinalis against renal toxicity induced by formaldehyde in rats. Thirty-six male albino rats with "Sprague Dawley" strain weighing (150±10 g) were used and split into 2 major groups, the first group (6 rats) fed on a basal diet and kept as a negative control, and the second group of 30 rats was injected with formaldehyde intraperitoneally (10 mg/kg BW /day on 14th to 28th day and divided into 5 subgroups. The first subgroup received a normal diet and acted as a positive control group. The second, third, fourth, and fifth categories consumed standard feed with oral dosages of 200 and 400 mg/Kg body weight per day of aqueous corn silk and asparagus aqueous extract respectively during a 28-day period.  Body weight gain (BWG), Feed intake (FI), feed efficiency ratio (FER), and relative kidney weight were computed at the finish of the experiment. Assessment of some serum biochemical parameters, kidney tissues were analyzed for antioxidant/oxidant markers, and histopathology of kidneys were assessed. The results revealed that corn silk and Asparagus aqueous extracts improved the biological evaluation, kidney functions, liver functions, Serum electrolytes, antioxidant enzymes activity, and histopathology of kidneys compared to the positive group. In conclusion, the administration of corn silk and Asparagus aqueous extracts can lower the impacts of formaldehyde on kidneys.

DOI

10.21608/bnni.2022.255461

Keywords

Corn silk, Asparagus, Formaldehyde, kidney functions, Antioxidant enzymes

Authors

First Name

Wafaa

Last Name

Abdel Hamid

MiddleName

Maher

Affiliation

Nutrition and Food Science Dept., Faculty of Home Economics, Al-Azhar University, Egypt

Email

-

City

Tanta

Orcid

-

First Name

Amira

Last Name

ElMoslemany

MiddleName

M

Affiliation

Nutrition and Food Science Dept., Faculty of Home Economics, Al-Azhar University, Egypt

Email

amiraelmoslemany@azhar.edu.eg

City

Tanta

Orcid

-

First Name

Neveen

Last Name

Zeima

MiddleName

M

Affiliation

Nutrition and Food Science Dept., Faculty of Home Economics, Al-Azhar University, Egypt

Email

-

City

Tanta

Orcid

-

Volume

60

Article Issue

2

Related Issue

36271

Issue Date

2022-12-01

Receive Date

2022-08-19

Publish Date

2022-12-01

Page Start

1

Page End

31

Print ISSN

1110-0974

Online ISSN

2537-0987

Article File

BNNI_Volume 60_Issue 2_Pages 1-31.pdf

PDF . 1.1MB

Link

https://bnni.journals.ekb.eg/article_255461.html

Detail API

https://bnni.journals.ekb.eg/service?article_code=255461

Order

255,461

Type

Original Article

Type Code

442

Publication Type

Journal

Publication Title

Bulletin of the National Nutrition Institute of the Arab Republic of Egypt

Publication Link

https://bnni.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023