Day by day, human faces many diseases that may depend on several factors including the lifestyle and genetic factors. After COVID-19 spreading, several sectors in our life are totally changed particularly the global medical system, which has been pushed to its breaking point. Furthermore, many human diseases, especially for the elderly and those with comorbidities, are at a great risk for adverse outcomes due to COVID-19 such as diabetes mellitus, hypertension severe obesity, and coronary disease. As one of the global top 10 deathly diseases, diabetes mellitus can cause many health complications including cardiovascular disease, chronic kidney disease, stroke, damage to the nerves, eyes and cognitive impairment. Beside the pharmaceutical treatments against diabetes, several functional foods (particularly honey and yogurt) could be fortified with many essential nutrients like copper, iodine, selenium, and zinc. These functions foods are rich in many bioactive ingredients, which support the human body to fight against such diabetes such as phenolic acids, flavonoids, vitamins and antioxidants. Feeding the human with yogurt mixed with the honey, which already has been fortified with many essential nutrients or vitamins, is important a new approach in fortification program again diseases like diabetes. This study opens new windows in the fortification field towards the human fighting against diseases like diabetes.