This work was aimed to study effect of C. intybus root extract on blood parameters of chicks under CCl4-induced toxicity. Totally, 240 one-day-old broiler chicks were divided into diverse groups of control, CCl4 (1 mL/kg body weight IM injection), C. intybus root extract (500 mg/kg body weight/daily orally from days 20 to 29) and finally both C. intybus and CCl4. Blood samples are collected daily from age of 20 to 31 days. Levels of alkaline phosphatase, aspartate aminotransaminase and alanine aminotransferase and glutathione peroxidase and superoxide dismutase were assessed by commercial kits. Decrease in the levels of AST and ALT and increase in the levels of SOD and GPx were observed. The lowest levels of AST, ALP and ALT in day 31 of blood sampling were achieved in chicks treated with C. intybus (500 mg/kg BW/daily from days 20 to 29) (130.91±31.18 U/L), CCl4 (1 mL/kg BW IM on days 24 and 25) (346.59±83.75 U/L) and C. intybus (from days 20 up to 29) (4.51±2.03 U/L) groups. The highest amounts of SOD and GPx in the stage 2 of blood sampling were achieved in chicks treated with C. intybus (500 from days 20 up to 29) and CCl4 (1 mL/kg BW on days 24 and 25) (590.33±73.22 U/L) and those treated with C. intybus (from days 20 up to 23) and CCl4 (on days 24 and 25) (261.91±32.18 U/L) groups, respectively. Oral prescription of chicory extract for 10 days can be used as a hepatoprotective agent on poultry.