A looking for natural coagulants for algal removal is one of the researchers' interests due to synthetic coagulants concerning different health problems. So, in this study, a comparative investigation was performed to determine the effect of Alum, FeCl3 as synthetic coagulants, and Moringa seed extract as a natural coagulant. The synthetic coagulants were prepared and Moringa seed has been watered extracted; all coagulants performed by Jar test at different doses for algal removal, and the effect of adding the powder activated carbon (PAC) derived from cotton stalk was tested as a coagulant aid.  The data revealed that all coagulants show good removal but the Moringa seed extract in addition to PAC exhibited the excellent result of removal reached 100%.