Facial wrinkle lines are due to aging, gravity, and chronic pulling of mimetic facial muscles. Primary focal hyperhidrosis is excessive sweating often affects the axilla, palms, soles, and forehead. This causes significant problems in private and professional life. Botulinum toxin is used in the treatment of facial wrinkles and hyperhidrosis as it inhibits the release of acetylcholine at the neuromuscular junction and in cholinergic sympathetic and parasympathetic neurons.